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1

The Scaffolding Adapter Gab1 Mediates Vascular Endothelial Growth Factor Signaling and Is Required for Endothelial Cell Migration and Capillary Formation

Laramee, M., Chabot, C., Cloutier, M., Stenne, R., Holgado-Madruga, M., Wong, A. J., Royal, I.

Journal:

Journal of Biological Chemistry

Year:

2007

Language:

english

File:

PDF, 1.04 MB

english, 2007

2

Development of an EGFRvIII specific recombinant antibody

Puja Gupta, Shuang-Yin Han, Marina Holgado-Madruga, Siddhartha S Mitra, Gordon Li, Ryan T Nitta, Albert J Wong

Journal:

BMC Biotechnology

Year:

2010

Language:

english

File:

PDF, 1.84 MB

english, 2010

3

Host adaptor proteins Gab1 and CrkII promote InlB-dependent entry of Listeria monocytogenes

Hong Sun, Yang Shen, Hatem Dokainish, Marina Holgado-Madruga, Albert Wong, Keith Ireton

Journal:

Cellular Microbiology

Year:

2005

Language:

english

File:

PDF, 414 KB

english, 2005

4

A Grb2-associated docking protein in EGF- and insulin-receptor signalling

Holgado-Madruga, Marina, Emlet, David R., Moscatello, David K., Godwin, Andrew K., Wong, Albert J.

Journal:

Year:

1996

File:

PDF, 1.51 MB

1996

5

Elevated JNK activation contributes to the pathogenesis of human brain tumors

Antonyak, Marc A, Kenyon, Lawrence C, Godwin, Andrew K, James, David C, Emlet, David R, Okamoto, Isamu, Tnani, Mehdi, Holgado-Madruga, Marina, Moscatello, David K, Wong, Albert J

Journal:

Year:

2002

Language:

english

File:

PDF, 264 KB

english, 2002

6

Proteolytic Cleavage of the CD44 Adhesion Molecule in Multiple Human Tumors

Isamu Okamoto, Hiromasa Tsuiki, Lawrence C. Kenyon, Andrew K. Godwin, David R. Emlet, Marina Holgado-Madruga, Irene S. Lanham, Christopher J. Joynes, Kim T. Vo, Abhijit Guha, Mitsuhiro Matsumoto, Yuki

Journal:

The American Journal of Pathology

Year:

2002

Language:

english

File:

PDF, 300 KB

english, 2002

7

Targeting a Glioblastoma Cancer Stem-Cell Population Defined by EGF Receptor Variant III

Emlet, D. R., Gupta, P., Holgado-Madruga, M., Del Vecchio, C. A., Mitra, S. S., Han, S.-Y., Li, G., Jensen, K. C., Vogel, H., Xu, L. W., Skirboll, S. S., Wong, A. J.

Journal:

Cancer Research

Year:

2014

Language:

english

File:

PDF, 1.19 MB

english, 2014

8

Grb2-Associated Binder-1 Mediates Phosphatidylinositol 3-Kinase Activation and the Promotion of Cell Survival by Nerve Growth Factor

Marina Holgado-Madruga, David K. Moscatello, David R. Emlet, Rebekka Dieterich and Albert J. Wong

Journal:

Proceedings of the National Academy of Sciences

Year:

1997

Language:

english

File:

PDF, 1.45 MB

english, 1997

9

Grb-2-Associated Binder-1 Is Involved in Insulin-Induced egr-1 Gene Expression through its Phosphatidylinositol 3′-Kinase Binding Site

Harada, Shuko, Esch, Gwyn L., Holgado-Madruga, Marina, Wong, Albert J.

Journal:

DNA and Cell Biology

Year:

2001

Language:

english

File:

PDF, 283 KB

english, 2001

10

A Conserved Inositol Phospholipid Binding Site within the Pleckstrin Homology Domain of the Gab1 Docking Protein Is Required for Epithelial Morphogenesis

Maroun, C. R., Moscatello, D. K., Naujokas, M. A., Holgado-Madruga, M., Wong, A. J., Park, M.

Journal:

Journal of Biological Chemistry

Year:

1999

Language:

english

File:

PDF, 770 KB

english, 1999

11

The Gab1 Docking Protein Links the B Cell Antigen Receptor to the Phosphatidylinositol 3-Kinase/Akt Signaling Pathway and to the SHP2 Tyrosine Phosphatase

Ingham, R. J., Santos, L., Dang-Lawson, M., Holgado-Madruga, M., Dudek, P., Maroun, C. R., Wong, A. J., Matsuuchi, L., Gold, M. R.

Journal:

Journal of Biological Chemistry

Year:

2001

Language:

english

File:

PDF, 886 KB

english, 2001

12

Association of the Multisubstrate Docking Protein Gab1 with the Hepatocyte Growth Factor Receptor Requires a Functional Grb2 Binding Site Involving Tyrosine 1356

Nguyen, L., Holgado-Madruga, M., Maroun, C., Fixman, E. D., Kamikura, D., Fournier, T., Charest, A., Tremblay, M. L., Wong, A. J., Park, M.

Journal:

Journal of Biological Chemistry

Year:

1997

Language:

english

File:

PDF, 959 KB

english, 1997

13

Constitutive Activation of Phosphatidylinositol 3-Kinase by a Naturally Occurring Mutant Epidermal Growth Factor Receptor

Moscatello, D. K., Holgado-Madruga, M., Emlet, D. R., Montgomery, R. B., Wong, A. J.

Journal:

Journal of Biological Chemistry

Year:

1998

Language:

english

File:

PDF, 386 KB

english, 1998

14

Gab1 Is an Integrator of Cell Death versus Cell Survival Signals in Oxidative Stress

Holgado-Madruga, M., Wong, A. J.

Journal:

Molecular and Cellular Biology

Year:

2003

Language:

english

File:

PDF, 566 KB

english, 2003

15

Role of the Grb2-Associated Binder 1/SHP-2 Interaction in Cell Growth and Transformation

Holgado-Madruga, M.

Journal:

Cancer Research

Year:

2004

Language:

english

File:

PDF, 412 KB

english, 2004

16

c-Jun NH2-Terminal Kinase 2 2 Promotes the Tumorigenicity of Human Glioblastoma Cells

Cui, J., Han, S.-Y., Wang, C., Su, W., Harshyne, L., Holgado-Madruga, M., Wong, A. J.

Journal:

Cancer Research

Year:

2006

Language:

english

File:

PDF, 495 KB

english, 2006

17

Efficient Cellular Transformation by the Met Oncoprotein Requires a Functional Grb2 Binding Site and Correlates with Phosphorylation of the Grb2-associated Proteins, Cbl and Gab1

Fixman, E. D., Holgado-Madruga, M., Nguyen, L., Kamikura, D. M., Fournier, T. M., Wong, A. J., Park, M.

Journal:

Journal of Biological Chemistry

Year:

1997

Language:

english

File:

PDF, 797 KB

english, 1997

18

The Gab1 Protein Is a Docking Site for Multiple Proteins Involved in Signaling by the B Cell Antigen Receptor

Ingham, R. J., Holgado-Madruga, M., Siu, C., Wong, A. J., Gold, M. R.

Journal:

Journal of Biological Chemistry

Year:

1998

Language:

english

File:

PDF, 949 KB

english, 1998

19

The Tyrosine Phosphatase SHP-2 Is Required for Sustained Activation of Extracellular Signal-Regulated Kinase and Epithelial Morphogenesis Downstream from the Met Receptor Tyrosine Kinase

Maroun, C. R., Naujokas, M. A., Holgado-Madruga, M., Wong, A. J., Park, M.

Journal:

Molecular and Cellular Biology

Year:

2000

Language:

english

File:

PDF, 2.31 MB

english, 2000

20

Determination of Gab1 (Grb2-Associated Binder-1) Interaction with Insulin Receptor-Signaling Molecules

Rocchi, Stéphane, Tartare-Deckert, Sophie, Murdaca, Joseph, Holgado-Madruga, Marina, Wong, Albert J., Van Obberghen, Emmanuel

Journal:

Molecular Endocrinology

Year:

1998

Language:

english

File:

PDF, 508 KB

english, 1998

21

The Gab1 PH Domain Is Required for Localization of Gab1 at Sites of Cell-Cell Contact and Epithelial Morphogenesis Downstream from the Met Receptor Tyrosine Kinase

Maroun, Christiane R., Holgado-Madruga, Marina, Royal, Isabelle, Naujokas, Monica A., Fournier, Tanya M., Wong, Albert J., Park, Morag

Journal:

Molecular and Cellular Biology

Year:

1999

Language:

english

File:

PDF, 10.18 MB

english, 1999

22

Grb2-associated binder-1 mediates phosphatidylinositol 3-kinase activation and the promotion of cell survival by nerve growth factor

Holgado-Madruga, M., Moscatello, D. K., Emlet, D. R., Dieterich, R., Wong, A. J.

Journal:

Proceedings of the National Academy of Sciences

Year:

1997

Language:

english

File:

PDF, 454 KB

english, 1997